The Vice-Chancellor is the Chief Executive Officer of the University with the overall responsibility for the development, management and maintenance of the academic, administrative and financial operations of the University. The office took off in October 2012 with the appointment of the Professor Adeniyi Agunbiade as the pioneer Vice-Chancellor of the University.
The second substantive Vice-Chancellor is Professor Francis Adegbaye Igbasan.
The office of the Vice-Chancellor has the following Units:
- The Main Office
- Information and Public Relations Unit
- Directorate of Academic Planning
- Directorate of Student Affairs
- Internal Audit Unit
- ICT Unit
- Sports Unit
- Security Unit.